A depiction of the port of Naples on 6 October 1759, when Charles of Bourbon (1716-1788) left for Spain, where he would reign under the name of Carlos III. son of Felipe V (1683-1746) and Isabel de Farnesio (1692-1776), Carlos was king of Naples and Sicily until his brother, Fernando VI (1713-1759) died without issue, obliging Carlos to return to Spain.

The scene shows the bay of Naples with the volcano of Vesuvius smoking in the backtround and ships leaving the ort. In the foreground, the Prime Minister, Marquis of Tanucci, is recognizable in a carriage among the crowd at the docks.

There are four known autograph versions of this work, one of which disappeared in the fire at the Spanish Embasy in Lisbon in 1975. It is paired with Carlos III leaving the Port of Naples, as seen from the Sea (P233).