This was one of Isabel de Bourbon's private devotional paintings. It's composition is outstanding for its balance and serenity, which calls for calm and intimate meditation.

While paintings and prints by various authors, including El Greco, Martin de Vos and even Rubens, have been cited as formal antecedents to this work, Velázquez's personal interpretation surpasses any affiliation.

Both the placement of the sacred figures and the Virgin's gesture, as well as the reddish tone of her robes may be a subtle allusion to the early cult of the Sacred Heart of Mary.

This work was painted for the chapel in the Queen's chambers at the Madrid's Alcázar Palace.