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The artist of this panel is traditionally referred to as the Master of the Luna Family, whom Post first identified in 1933 as one of the two painters who produced the altarpiece for the chapel of Saint James the Apostle in Toledo Cathedral, founded by Don Álvaro de Luna. It was the latter`s daughter, María de Luna, Duchess of El Infantado, who contracted the altarpiece on 21 December
This painting is a slight variation of the central panel in the predella of the Don Álvaro de Luna Altar Piece which is in the Toledo cathedral (doc. 1488). Mary, helped by Saint John and Nicodemus, is in front of the cross holding her dead son. Joseph of Arimathea, Mary Magdalene and two Marys also show their sorrow. This painting is a pair with The Virgin of Milk (P-1289).
Figura de cuerpo entero, con el niño en brazos; un joven donante arrodillado; fondo de paisaje. En el marco, el escudo. Presenta analogías con tablas vallisoletanas influidas por Pedro Berruguete. Díaz Padrón y Alonso Blázquez lo atribuyen al maestro de don Álvaro de Luna.
