Nebbia was a prolific painter and draftsman, a student under Girolamo Muziano (1532-1592), but influenced also by Federico Zuccaro (1540/42-1609). Between 1562 and 1575 he worked continuously as a frescoist in the cathedral at Orvieto, for which he also executed altarpieces. He subsequently moved to Rome, where again he produced altarpieces for various churches, as well as decorations at the Sforza Chapel, S. Maria Maggiore (1582) and the Borghese Chapel, S.Trinita dei Monti (c. 1590). In collaboration with Giovanni Guerra (1544-1618) he carried out decorations in the Sistine Library and the Scala Santa in S. Giovanni in Laterano, at the same time as he painted other works in the Lateran. In 1597 Nebbia was head of the Accademia di S. Luca, which he had belonged to as early as 1579, soon after his arrival in the city. He returned to Orvieto in 1609 (Turner, N.: From Michelangelo to Annibale Carracci. A century of Italian drawings from the Prado, Art Services International-Museo Nacional del Prado, 2008, p. 126).