This altarpiece consists of nine large panels plus the eighteen that make up the predella. The main scene is The Virgin with the Christ Child surrounded by Angel Musicians, which is completed with five scenes from the lives of Christ and the Virgin in the right and central areas, and three scenes from the life of saint Francis, in the left area. All of them are framed with gothic ogee tracery.

Stylistically, the panels correspond to the so-called international gothic, which combines the Italian taste for narrative clarity with the northern attraction to naturalist details. The conception of this altarpiece is in keeping with the interest in representing reality that began in the gothic era.

It was painted for a chapel near the town of La Bañeza in León.

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