A native of the province of Nursia, the holy abbot that founded the Benedictine Order in the sixth century appears inside his cell, where he witnesses the apparition of a globe held by three angels in the presence of the Trinity.

This work denotes the Venetian influences which Cano absorbed in court, allowing him to create a canvas characterized by a magnificent use of paint, resolving colors with warm tones in order to transmit the experience of his vision. He even goes so far as to alter anatomical orthodoxy for expressive purposes, as can be seen in the Saint's extremely long fingers, which he depicts with a great economy of means. At the same time, the fine and confident rendering of the face shows that he is one of the most powerful draftsmen of his time.