Seated on a throne under Renaissance architecture, the Virgin holds the Christ Child on her lap. On the left is Saint Benedict and on the right, Saint Bernard, the two patrons of the Order of Montesa. The smaller figure, who commissioned this work, is probably Luis Despuig, the Order's Grand Master between 1472 and 1482 and Viceroy of Valencia between 1472 and 1478.

While the color scheme of the Virgin's clothing is cloer to that of Venetian artists, it is clear that Paolo de San Leocadio was trained in the school of Ferrara. An example of this is his application of light and shadows to the other figures and to the background, where the shapes are not as soft.