The Christ Child plays with a book in Mary's lap, a clear allusion to the Holy Scriptures that announce Christ's redemptive mission. Above, an angel crowns Mary.

The two figures placed under a niche with gothic tracery recall that same artist's Descent from the Cross (P02825). Moreover, the neutral background and strongly plastic character of the figures, with their considerable volume, makes them look like polychrome sculptures.

Also known as the Madonna in Red or Durán Madonna, this is unanimously considered an original work by Van der Weyden, though numerous versions existed in Spain. A work of great intimacy and technical quality, it is outstanding among his pieces and bears the influence of his teacher, Robert Campin.