Alfonso de Castro, O.F.M., (1495 in Zamora, Spain – 3 February 1558 in Brussels, Belgium) known also as Alphonsus à Castro, was a Franciscan theologian and jurist. He belongs to the group of theologian-jurists known as the School of Salamanca (otherwise identified as Spanish Late Scholasticism), though he denied belonging to a specific school of thought and condemned many theologians who did. He was most well-known in the sixteenth century for his work Adversus omnes haereses, libri XIV, an encyclopedic treatise on ancient and modern heresies.

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