Rincón worked in Aragon but primarily in Castile where he contributed to introducing the Renaissance style. This large-format panel from Guadalajara combines a Renaissance spatial approach and forms with medieval elements such as the profusion of elaborate brocade fabrics. The panel depicts two of the miracles of Cosmas and Damian, twins who promoted both medicine and Christianity: the replacement of a gangrenous leg with a healthy one taken from a corpse and the expulsion of a snake from the body of a reaper.